Overview
GHRP-6 is listed in PubChem as Growth hormone releasing hexapeptide (CID 9919153), with the molecular formula C46H56N12O6 and a molecular weight of 873.0 g/mol. PubChem lists its sequence as His-D-Trp-Ala-Trp-D-Phe-Lys-NH2, a 6-residue peptide. Other names in PubChem include GH-releasing peptide-6, Hexapeptide-2, SKF-110679. It is supplied as a lyophilized powder in sealed 5 mg and 10 mg vials.
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Molecular profile
| PubChem name | Growth hormone releasing hexapeptide |
|---|---|
| Also known as (PubChem) | GH-releasing peptide-6, Hexapeptide-2, SKF-110679 |
| Sequence | His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 |
| Length | 6 residues |
| Residue composition | Ala, D-Phe, D-Trp, His, Lys, Trp |
| Molecular formula | C46H56N12O6 |
| Molecular weight | 873.0 g/mol |
| CAS number | 87616-84-0 |
| PubChem CID | 9919153 |
Computed properties (PubChem)
| Exact mass | 872.4446 Da |
|---|---|
| Monoisotopic mass | 872.4446 Da |
| XLogP3 | 1.9 |
| Topological polar surface area | 301 Ų |
| Hydrogen bond donors | 11 |
| Hydrogen bond acceptors | 9 |
| Rotatable bonds | 23 |
| Heavy atoms | 64 |
| Formal charge | 0 |
| Complexity | 1570 |
| Defined stereocenters | 6 of 6 |
Identifiers (PubChem)
| InChIKey | WZHKXNSOCOQYQX-FUAFALNISA-N |
|---|---|
| SMILES | C[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC3=CC=CC=C3)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@@H](CC4=CNC5=CC=CC=C54)NC(=O)[C@H](CC6=CN=CN6)N |
| UNII | 4H7N4I6X6A |
| ChEMBL ID | CHEMBL105462 |
IUPAC name (PubChem)
(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
Source: PubChem compound 9919153